When our application and libraries references reaches their limits, then we get some errors that shows we reached the limit of built architecture.

Like this

trouble writing output:
Too many field references: 131000; max is 65536.
You may try using --multi-dex option.

So we need to configure Multidex with Gradle

This plugin available for Android SDK Build Tools 21.1 and higher for Gradle. We need to do just small modifications for it.

There is the modification in gradle file.
add one dependency for multidex and enable multiDex in defaultConfig.

android {
    compileSdkVersion 21
    buildToolsVersion "21.1.0"

    defaultConfig {
        ...
        minSdkVersion 14
        targetSdkVersion 21
        ...

        // Enabling multidex support.
        multiDexEnabled true
    }
    ...
}

dependencies {
  compile 'com.android.support:multidex:1.0.0'
}

In manifest, just add MultiDexApplication class to the application element.

<?xml version="1.0" encoding="utf-8"?>
<manifest xmlns:android="http://schemas.android.com/apk/res/android"
    package="com.example.android.multidex.myapplication">
    <application
        ...
        android:name="android.support.multidex.MultiDexApplication">
        ...
    </application>
</manifest>