By default Ghost uses sqlite3. But if you want to configure Ghost with MySQL Database, you can reconfigure the default settings in config.js file.

Open config.js (<path-to-your-project>/config.js), replace the below lines of code:

database: {
    client: 'sqlite3',
    connection: {
        filename: path.join(__dirname, '/content/data/ghost2.db')
    },
}

with the MySql configuration. Here is the syntax:

database: {
        client: 'mysql',
        connection: {
            host: 'localhost',
            user: 'database-user',
            password: 'database-user-password',
            database: 'database-name',
            charset: 'utf8'
        },
}

Note: Replace database-user, database-user-password and database-name with the actual details.