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Adderall is a combination medicine containing amphetamine and dextroamphetamine. It is generally well-tolerated and effective in treating the symptoms of ADHD and narcolepsy. At therapeutic doses, Adderall often causes emotional and cognitive effects such as euphoria, change in sex drive, increased wakefulness, and improved cognitive control.

At these doses, Adderall induces physical effects such as fatigue resistance, a faster reaction time, and increased muscle strength. In contrast, significantly larger amounts of Adderall can cause rapid muscle breakdown, impair cognitive control, provoke panic attacks, or induce a psychosis (e.g., hallucinations, paranoia, delusions). When given for ADHD, Adderall should be used in conjunction with other treatment strategies, such as psychotherapy, social integration advice, and education about the disorder. FDA has approved the use of Adderall in children over the age of three.