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A person suffering from moderate to severe pain may receive a prescription from the doctor for the combination of the generically named medicines acetaminophen and oxycodone. Perloxx can make the person produce abnormal stools while using the medicine. It may turn the stools to the consistency and color of tar. It also can cause the person's stools to appear lighter than normal in color. Either of these side effects needs immediate medical intervention, Mayo Clinic indicates. Like most narcotic pain relievers, the oxycodone in Perloxx can cause the person to find it difficult to focus her vision, Drugs.com Indicates. She may have trouble with near or far object recognition, or it may occur as a general blurriness.